American Heart Association

Remembering Cass Wheeler

Visionary leader Cass Wheeler leaves enduring legacy in the fight against heart disease and stroke

Cass Wheeler's transformational leadership touched millions of lives. The American Heart Association honors his legacy and his vision to advance health and hope for everyone, everywhere.

The American Heart Association is celebrating the life and legacy of its former Chief Executive Officer, Cass Wheeler, who led the Association for more than three decades with extraordinary commitment and compassion. Wheeler, a long-time Georgetown, Texas resident, passed away peacefully from ALS, a progressive neurodegenerative disease. He was 84.

Cass Wheeler served as CEO of the American Heart Association, a global force changing the future of health for all, from 1998 until his retirement in 2008, capping a 35-year tenure with the organization. His leadership marked a transformational era for the Heart Association, guiding the nonprofit into the 21st century and dramatically expanding its global influence in public health, cardiovascular science, fundraising and community engagement.

“Cass Wheeler was more than a leader — he was a mentor, a dear friend, and a relentless champion for every person at risk of cardiovascular disease,” said Nancy Brown, CEO of the American Heart Association. “He believed deeply in the power of purpose, and he inspired generations of staff and volunteers to push beyond boundaries. I would not be where I am today without his guidance and belief in me. His legacy lives in the millions of lives touched by the work he helped build.”

At the family's request, donations can be made to the American Heart Association in honor of Cass Wheeler’s lifelong dedication to building health and hope, for everyone everywhere.

Cass Wheeler with United States Capitol Building in background