Clinical Research Studies
American Heart Association/American Stroke Association offers the opportunity to be included in clinical research studies:
What is ARAMIS?
Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS) Registry is designed to provide important and timely insight into the management of acute stroke patients who are on novel oral anticoagulants in community practice. The AHA work in partnership with Duke Clinical Research Institute(DCRI) to promote this Registry. Building upon the existing infrastructure of the nation’s largest ongoing stroke registry (American Heart Association/American Stroke Association Get With The Guidelines - Stroke), the ARAMIS registry will be a multicenter, prospective, observational study of AIS and ICH patient on home anticoagulation therapy.
The ARAMIS registry is fully observational and there is no treatment or management strategies directed by the study protocol. All treatment decisions are at the discretion of the treatment physicians.
What is CHANGE AFib?
CHANGE AFib is the first pragmatic trial to focus on identifying treatment best practices for first-detected AFib. The trial seeks to determine whether early treatment with the antiarrhythmic drug dronedarone in patients presenting to the hospital with first-detected atrial fibrillation is more effective than usual care for the prevention of unplanned cardiovascular hospitalization or death from any cause, and may result in improved cardiovascular and long-term outcomes. CHANGE AFib is a collaboration between the American Heart Association®, and the Duke Clinical Research Institute (DCRI), with support from Sanofi US.
What is the PCORI Funded Guided Heart Failure Study?
GWTG Interventions to Reduce Disparities in AHF Patients Discharged from the ED (GUIDED HF)
With support from a three-year, $2 million research grant from Patient-Centered Outcomes Research Institute (PCORI), Vanderbilt University Medical Center and the American Heart Association are teaming up to study heart failure care in the Emergency Department.
What was PROSPER?
Patient-centered Research into Outcomes Stroke Patients prefer and Effectiveness Research (PROSPER) was a multi-center study that evaluated post-discharge functional status, disability, depression and quality of life in stroke survivors. Learn more about the PROSPER study here.
