The use of lidocaine associated with an improvement in the rate of ROSC

Updated:Mar 13,2014
American Heart Association/American Stroke Association
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The use of lidocaine associated with an improvement  in the rate of return of spontaneous circulation (ROSC) and 24-hour survival in pediatric cardiac arrest patients
 
Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation. Santiago O. Valdes, Aaron J. Donoghue, Derek B. Hoyme, Rachel Hammond, Marc D. Berg, Robert A. Berg, Ricardo A. Samson. Resuscitation.
Key Points:
  • This is the first study analyzing outcomes of anti-arrhythmic medication use in pediatric cardiac arrest
  • Study evaluated the impact on outcomes from the use of lidocaine, amiodarone, or a combination of both in 889 pediatric cardiac arrest patients over an 8 year period.  
  • The use of lidocaine in pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation independently resulted in an increased rate of return of spontaneous circulation (ROSC) and 24-hour survival.
  • The use of amiodarone in pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation use was found to not be associated with an improvement in either ROSC or 24-hour survival.
  • The outcome of survival to hospital discharge was not improved by the administration of lidocaine or amiodarone in pediatric cardiac arrest patients.
 
 
Picture of Santiago ValdesDr. Santiago O. Valdes is an Assistant Professor in the Section of Pediatric Cardiology Electrophysiology and Pacing at Baylor College of Medicine and Texas Children's Hospital. He attended Medical School at the University of Texas Health Science Center in Houston. Finished Pediatric Residency and Chief Residency at the University of Arizona. Completed Pediatric Cardiology Fellowship and Electrophysiology Fellowship at Baylor College of Medicine and Texas Children's Hospital. Was an Assistant Professor at the University of Arizona for 5 years prior to returning to Baylor College of Medicine and Texas Children's Hospital. Research focus is the management of arrhythmias in the Pediatric population particularly ventricular fibrillation in pediatric resuscitation.
 
Dr. Ricardo Samson is Professor in the Cardiology Section, Department of Pediatrics at The University of Arizona. He attended medical school at the University of Michigan, completed residency at The University of Arizona and fellowships in pediatric cardiology at the University of Iowa and pediatric electrophysiology at Northwestern University. Dr. Samson’s research interests have focused on resuscitation and, in particular, ventricular fibrillation and defibrillation in pediatric patients. He has been a member of the Emergency Cardiovascular Care Committee of the American Heart Association and has served as Associate Science Editor for the 2011 Pediatric Advanced Life Support (PALS) course and its associated educational products.