Variant angina can also be called, Prinzmetal angina, Prinzmetal's variant angina, angina inversa. Unlike typical angina – which is often triggered by exertion or emotional stress - Prinzmetal’s angina almost always occurs when a person is at rest, usually between midnight and early morning. These attacks can be very painful. The pain from variant angina is caused by a spasm in the coronary arteries (which supply blood to the heart muscle).
The spasms tend to come in cycles – appearing for a time, then going away. After six to 12 months of treatment, doctors may gradually reduce the medication.