Cholesterol-lowering drugs reduce LDL cholesterol (known as the "bad cholesterol) and increase HDL cholesterol (the "good" kind). These drugs also reduce triglycerides (a blood fat). Several drugs are used to treat cholesterol, including statins. Cholesterol-lowering drugs have been proven to reduce risks for heart disease. Due to potential side effects, patients taking most cholesterol-lowering drugs may need to have periodic liver function tests.